Drugs, genes, peptides and other bioactive molecules can be delivered to target cells and organs for the treatments of diseases such as cancers, diabetes and asthma and for responding to specific biological stimuli. Pulmonary delivery of drug, gene and protein in nanocarrier systems is a major area of interest, since the action of a drug entrapped in nanocarriers may exhibit prolonged residence time in the lung after inhalation, potentially reducing systemic side effects. We are also interested in developing nanocarrier systems for nasal delivery aiming to treat local nasal diseases (e.g. sinusitis) and systemic diseases (e.g. diabetes, hormone deficiencies etc.). Synthesis properties, computer modelling and applications of a range of functionalised nanocarriers such as dendrimers, liposomes, carbon nanotubes, cochleates and niosomes are being investigated, particularly in the area of aerosol delivery.
UBTS Limited is currently undertaking a project with Sichuan University relating to Nanotechnology for Drug Delivery mechanisms. The aims of this project are:
Dr Abdelbary Elhissi is a Senior Lecturer in Pharmaceutics in UCLan’s School of Pharmacy and Biomedical Sciences. Abdelbary’s research is mainly focused on nanomedicines for respiratory drug delivery and the medical applications of nano and biomaterials. He is particularly interested in designing proliposome formulations for treatment of asthma and cancer. Abdelbary is also interested in clinical pharmaceutics and researching the contemporary issues of pharmacy education. He has been involved in research collaboration projects in UK, China and Middle East and has supervised more than 15 postgraduate students and more than 35 project students.